A psychic leads archaeologists into an Aztec pyramid, where they discover two mummies. One of these is a werewolf mummy. Both mummies revive and stalk the scientists. The werewolf mummy is played by Lon Chaney, Jr. in footage from La Casa del Terror, his last film role as a werewolf.

The film’s lack of story cohesion is what inspired a surrealist novel of the same title. Published in 2006, Face of the Screaming Werewolf by Ken Gage recycled imagery and dialogue from the film to tell a strange story involving Satan’s war in heaven, robots, sadomasochistic vampires, the nature of elitism, and aliens.